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A Case of Variegate Porphyria in Association With Coeliac Disease and Bisphosphonate Associated Dental Osteonecrosis

机译:一例与腹腔疾病和双膦酸盐相关的牙齿骨坏死相关的斑叶紫癜一例

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摘要

This case describes an older patient with a rare diagnosis of variegate porphyria presenting with acute abdominal pains and bloating, intermittent loose stools and jaw pains following surgical repair of an osteoporotic hip fracture. She was noted to have acute hyponatraemia. All the abdominal symptoms and the hyponatraemia were initially attributed to an acute episode of variegate porphyria with an accompanying syndrome of inappropriate antidiuretic hormone secretion. However, following further evaluations necessitated by the incomplete resolution of the abdominal symptoms, it became apparent that some of the persisting symptoms were due to a concurrent and new presentation of serology positive coeliac disease. The jaw pains were established to be due to dental osteonecrosis in association with the use of bisphosphonate therapy for treatment of osteoporosis. The various symptoms and signs subsequently settled uneventfully following institution of appropriate management options for the various coexisting diagnoses.
机译:该病例描述了一位老年患者,很少诊断出杂色卟啉症,在手术治疗骨质疏松性髋部骨折后出现急性腹痛和腹胀,间歇性大便稀疏和下巴疼痛。注意到她患有急性低钠血症。所有腹部症状和低钠血症最初归因于杂色卟啉症的急性发作,并伴有抗利尿激素分泌不当的综合症。然而,由于腹部症状的不完全解决而需要进行进一步的评估后,很明显,一些持续存在的症状是由于并发新出现的血清学阳性腹腔疾病。颌骨疼痛被确定是由于牙齿坏死,以及使用双膦酸盐治疗骨质疏松症所致。在为各种共存诊断制定适当的管理方案之后,各种症状和体征随后得到了平稳解决。

著录项

  • 作者

    Ogundipe, Olayinka A.;

  • 作者单位
  • 年度 2009
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  • 原文格式 PDF
  • 正文语种 {"code":"en","name":"English","id":9}
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